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2009-2010 FSU Graduate Bulletin

Biomedical Sciences

College of Medicine

Chair: David Balkwill; Professors: Balkwill, Galasko, Hurt, Klatt, Levitt, McGee, Meredith, Ouimet, Overton, Patrick, Payer, Rill; Associate Professors: Blaber, Horabin, Olcese, Yu; Assistant Professors: Altmann, Gunjan, Kabbaj, Kato, Lee, Stefanovic, VanLandingham, Wang; Assistant Scholar Scientist: Bienkienwicz; Assistants in Medicine: Cappendijk, Didier, Paik

The Department of Biomedical Sciences is a community of scholars dedicated to educating future physicians and scientists and advancing knowledge through discovery.

The PhD in Biomedical Sciences at the Florida State University College of Medicine is designed to train modern biomedical scientists who use genomics, proteomics, bioinformatics and other contemporary approaches to address questions of developmental, cell and molecular biology related to human health. The program is appropriate for students with majors in biochemistry, biology or other health-related fields. Three broad areas of research are emphasized: development, neuroscience and the molecular basis of human disease. Research rotations during the first year allow students to make an informed choice regarding the research area and major professor with whom they will conduct their PhD work. A core curriculum of the fundamentals, the choice of electives from other departments and intellectual interaction with faculty and postdoctoral fellows encourage graduate students to mature into independent scientists.

Admission Requirements

To apply for the PhD in Biomedical Sciences Program, students should contact the College of Medicine's Office of Research and Graduate Programs at (850) 644-2015 or visit the program's Web site (http://med.fsu.edu/biomed/phd/contact.asp) for other contact information. A prospective candidate must 1) have or be a candidate for a baccalaureate degree from an accredited college or university and be in good standing at the last institution attended, 2) have a minimum GPA of 3.0 (on a 4.0 scale), and 3) have a minimum combined verbal and quantitative score of 1000 or above on the Graduate Record Examinations (GRE). A GRE Subject Test is strongly recommended and may include Biochemistry and Cell Biology, General Biology, Chemistry or Physics. Applicants whose native language is not English and who have not received a degree from an English language institution are required to take the Test of English as a Foreign Language (TOEFL), receiving a minimum score of 600 for the paper test or 233 for the Computer Based Test (CBT). Special admission consideration may be requested for students with disabilities. Applicants must also send all required material to the University Admission Office at https://admissions.fsu.edu/gradapp/.

Degree Requirements

The College of Medicine grants the PhD in Biomedical Sciences through an interdisciplinary program with the goal of training students to conduct research in the broad area of the molecular basis of human disease, including the function of the human genome in development, neurobiology, aging, cancer and other disease.

The curriculum for the Biomedical Sciences degree includes core courses in statistics and ethics in research, as well as specialized biomedical course work and laboratory research. The direction and supervision of graduate work at the doctoral level resides primarily with the major professor and supervisory committee, which is comprised of four faculty members. Laboratory rotation in at least three laboratories during the first year is a degree requirement, designed to assist students in making informed choices regarding their courses of study.

To be considered for graduation from the College of Medicine with the PhD in Biomedical Sciences, the student must successfully complete all course requirements within five (5) calendar years from the time the student gains admittance to candidacy by passing the preliminary exam. Other requirements for graduation include attending the Health Science Seminar Series; teaching at least two (2) semesters; successfully completing the preliminary doctoral examination; submitting a doctoral research proposal approved by the major professor and the supervisory committee after admission to doctoral candidacy; registering for a minimum of twenty-four (24) semester hours of dissertation credit; and submitting, publicly presenting and successfully defending a doctoral dissertation.

Additional details are available at http://www.med.fsu.edu/biomed/phd/default.asp. Also, for complete details of degree requirements, plus a description of the college, its facilities, opportunities and available financial assistance, refer to the "College of Medicine" chapter of this Graduate Bulletin.

Definition of Prefixes

BMS—Basic Medical Sciences

GMS—Graduate Medical Sciences

IHS—Interdisciplinary Health Sciences

Graduate Courses

BMS 5185r. Research Opportunities in Biomedical Sciences (1–4). (S/U grade only.) Prerequisite: Admission to the Biomedical Sciences graduate program. This course provides entering students in the PhD Program in Biomedical Sciences opportunities to be informed of and receive training in research by rotating through the laboratories of several individual faculty members in the department. Students must complete three (3) laboratory rotations. Students should register for two (2) semester hours of credit for each seven (7) week rotation. May be repeated to a maximum of eight (8) semester hours.

BMS 5186C. Research Techniques in Biomedical Sciences (4). Prerequisites: BMS 5525, PCB 5137, and PCB 5595. This is an advanced laboratory course for students in the PhD Program in Biomedical Sciences, providing training in laboratory techniques and experimental approaches essential to contemporary molecular biology and biochemistry research.

BMS 5525. Bioregulation (4). Prerequisite: PCB 5595. This is an advanced, lecture-based course emphasizing the molecular basis of regulation in biological systems. An important component is the study of the design and interpretation of experiments leading to understanding of regulation of gene expression. The course relies on contemporary research literature and focuses on specific model organisms and current problems that illustrate experimental approaches used to investigate different aspects of the control of gene expression.

BMS 5905r. Directed Independent Study in Biomedical Sciences (1–12). (S/U grade only.) Prerequisite: Admission to the Biomedical Sciences graduate program. This is an individualized research course intended for students in the PhD Program in Biomedical Sciences prior to passing the Preliminary Doctoral Examination. May be repeated to a maximum of fifty-four (54) semester hours.

BMS 5935r. Advanced Topics in Biomedical Sciences (1–2). (S/U grade only.) Prerequisite: Admission to the Biomedical Sciences graduate program. This is a seminar-based course in which students in the PhD Program in Biomedical Sciences present seminars on current research from the literature on topics developed under the guidance of faculty members. Students critically read, analyze, and present current research. May be repeated to a maximum of eight (8) semester hours.

BMS 6900r.Directed Individual Study in Biomedical and Clinical Sciences (2–9). (S/U grade only.) This course involves supervised individual study on selected topics. May be repeated to a maximum of eighteen (18) semester hours in the same term.

BMS 6936r. Seminar in Biomedical Sciences (1–2). (S/U grade only.) A seminar series in current topics in biomedical sciences. May be repeated to a maximum of sixteen (16) semester hours.

GMS 5905r. Directed Individual Study (1–3). (S/U grade only.) Prerequisite: Instructor permission. Study on a selected topic as designated by the student or directing professor. May be repeated to a maximum of nine (9) semester hours.

GMS 6001r. Special Topics in Biomedical Sciences (1–3). (S/U grade only.) An expert, lecture-based course with focus on recent advances and outlooks in Biomedical Sciences research. Course offerings include but are not limited to such topics as aging, biotechnology, bioinformatics, developmental biology, genomics and proteomics, molecular signaling, neuroscience, and physiology. The general emphasis is on the molecular, genetic and cell biology aspects of these topics. May be repeated to a maximum of sixteen (16) semester hours.

GMS 6097Cr. Biomedical Sciences Research (3). Laboratory course designed to provide students with individualized instruction in specific experimental strategies and methods important to their chosen specialty area of biomedical research training. May be repeated to a maximum of twelve (12) semester hours.

IHS 5503r. Proposal Development (1). (S/U grade only.) Individualized instruction for graduate students in the College of Medicine in the development of a dissertation proposal or other proposals, including the strategies, process and requirements that meet the standards for written project proposals in medical research. May be repeated to a maximum of two (2) semester hours.

IHS 5515. Ethics and Professional Integrity in Research (1). (S/U grade only.) This is a required course for students in the PhD Program in Biomedical Sciences. This course provides a survey of three broad areas of research ethics: issues raised by using animals in research, using people in research, and by the scientific method itself. The course presents examples of ethical decisions faced in medical research, including ascribing credit for contributions in publications, consequences of plagiarism and fraudulent data, access to genetic data, confidentiality, institutional review boards and considerations in research involving animal or human subjects.

IHS 5905r. Directed Individual Study in Health Sciences (1-12). (S/U grade only.) This is a course for graduate students who desire an individualized research experience in Biomedical Sciences, Medical Humanities and Social Sciences, Public Health or other fields represented in the College of Medicine. Students receive laboratory or other training in research methods and improve their readiness for and appreciation of research in health-related science. May be repeated to a maximum of thirty-six (36) semester hours.

IHS 5906r. Directed Individual Study in Medical Sciences (1–12). (S/U grade only.) This is a course for medical students who desire an individualized research experience in Biomedical Sciences, Medical Humanities and Social Sciences, Public Health or other fields represented in the College of Medicine. Students receive laboratory or other training in research methods and improve their readiness for and appreciation of independent research in health-related science. May be repeated to a maximum of twenty-four (24) semester hours.

IHS 5933. Seminar on Medical Science Education (1). (S/U grade only.) Preparation for supervised teaching and education outreach experiences. Topics include approaches to conduct of classes and laboratories, exam construction, ethics in teaching, legal and safety issues for instructors, and effective written and oral communication.

IHS 5935r. Health Sciences Seminar (1). (S/U grade only.) This is a seminar program for students in the Ph.D. Program in Biomedical Sciences and other health-related programs. Biomedical Sciences students are required to enroll each Fall and Spring semester. May be repeated to a maximum of twelve (12) semester hours.

IHS 5945r. Supervised Teaching (1–5). (S/U grade only.) Students in the Ph.D. Program in Biomedical Sciences are required to register for a minimum of two (2) semester hours before graduation. May be repeated to a maximum of five (5) semester hours.

IHS 6980r. Dissertation Research (1–12). (S/U grade only.) Ph.D. candidates in Biomedical Sciences should register for this course after passing the Preliminary Examination. A minimum of twenty-four (24) dissertation hours is required for graduation.

IHS 8960r. Preliminary Doctoral Examination (0). (P/F grade only.) Oral examination and defense of the doctoral proposal; successful completion allows advancement of the student to Ph.D. candidacy.

IHS 8970r. Dissertation Defense (0). (P/F grade only.) Oral defense of dissertation research. One-time registration during the term in which the student expects to defend their Ph.D. dissertation.